SH2 domain

"SH2" redirects here. For the microprocessor, see SuperH. For State Highway 2, see list of highways numbered 2. The Src homology 2 domain (or SH2 domain) is a protein domain of about 100 amino acid residues first identified as a conserved sequence region among the oncoproteins Src and Fps. Similar sequences were later found in many other intracellular proteins involved in signal transduction, such as Abl, ZAP70, STAT proteins,Grb2, and RasGAP.
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