Cholestyramine or colestyramine (Questran®, Questran Light®, Cholybar®) is a
bile acid sequestrant, which binds
bile in the
gastrointestinal tract to prevent its reabsorption. The resin is a strong anion exchange resin, which means that it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer.
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