Hematopoietic stem cell
Hematopoietic stem cells (HSC) are
stem cells which give rise to all the blood cell types including
myeloid (
monocytes and
macrophages,
neutrophils,
basophils,
eosinophils,
erythrocytes,
megakaryocytes/
platelets,
dendritic cells) and
lymphoid lineages (
T-cells,
B-cells,
NK-cells). The definition of hematopoietic stem cells has undergone considerable revision in the last two decades. The hematopoietic tissue contains cells with long term and short term regeneration capacities and committed multipotent, oligopotent and unipotent progenitors. Recently, long-term transplantation experiments point towards a clonal diversity model of hematopoietic stem cells. Here, the HSC compartment consists of a fixed number of different types of HSC, each with
epigenetically preprogrammed behavior. This contradicts older models of HSC behavior, which postulated a single type of HSC that can be continuously molded into different subtypes of HSC.
See more at Wikipedia.org...
Komórka macierzysta hemopoezy
© W niniejszym artykule wykorzystano materialy pochodzace z
Wikipedia® i posiada on Powszechna
Licencje Publiczna GNU
Гемоцитобласт