Pleiotropy

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pleiotropy
n. capacity of a isolated allele to have more than one distinguishable effect


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Pleiotropy
Pleiotropy occurs when a single gene influences multiple phenotypic traits. Consequently, a new mutation in the gene will have an effect on all traits simultaneously. This can become a problem when selection on one trait favours one specific mutant, while the selection at the other trait favours another mutant.
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Common Terms in Evolutionary Biology and Genetics DictionaryDownload this dictionary
Pleiotropy
More than one effect of a gene on the phenotype. The effects may occur simultaneously or sequentially. An example is the determination of the color pattern and the shape of the eyes by a single allele in Siamese cats. Another example is the DNA repair enzymes which have several other functions (transcription, cell cycle regulation, regulation of gene rearrangements).

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pleiotropy
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