Peutz-Jeghers Syndrome

Peutz-Jeghers, also known as Hereditary Intestinal Polyposis Syndrome, is an autosomal dominant genetic disease.
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PJS. A genetic disorder in which polyps form in the intestine and dark spots appear on the mouth and fingers. Having PJS increases the risk of developing gastrointestinal and many other types of cancer.

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This consists of mucocutaneous pigmentation (circumoral, hands and feet) and gastrointestinal polyps and has a mendelian dominant inheritance.