Parkinson's disease

n. nervous disease characterized by trembling and lack of muscle control (causing difficulty of speech and of movement)

Parkinson's disease (also known as Parkinson disease or PD) is a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills and speech. Parkinson's disease belongs to a group of conditions called movement disorders. It is characterized by muscle rigidity, tremor, a slowing of physical movement (bradykinesia) and, in extreme cases, a loss of physical movement (akinesia). The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Secondary symptoms may include high level cognitive dysfunction and subtle language problems. PD is both chronic and progressive.
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Noun
1. a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination
(synonym) paralysis agitans, Parkinsonism, Parkinson's syndrome, Parkinson's, shaking palsy
(hypernym) brain disorder, encephalopathy, brain disease
(part-meronym) tremor

Parkinson's disease is an abnormal condition of the nervous system caused by degeneration of an area of the brain called the basal ganglia. The disease results in rigidity of the muscles, slow body movement and tremor. Parkinson's disease is also called "paralysis agitans" and "shaking palsy."

A progressive disorder of the nervous system marked by muscle tremors, muscle rigidity, decreased mobility, stooped posture, slow voluntary movements, and a mask-like facial expression.