Osei Kofi Tutu I was one of the co-founders of the Empire of Ashanti, the other being Okomfo Anokye, his chief priest. The Ashanti were a powerful, warlike, and highly disciplined people of West Africa. Osei Tutu led an alliance of Ashanti states against the regional hegemon, the Denkyira, completely defeating them. Then, through force of arms and diplomacy, he induced the rulers of the other Ashanti city-states to declare allegiance to Kumasi, his capital. Throughout his career he was politically advised by Anokye, a cleric whose spiritual authority over the people aided in his founding of the empire.

Osei Tutu I., eigentlich Otumfoe Osei Nana Kofi Tutu I., (* 16??; † 1717) war der Gründer des  Königreichs der Ashanti im heutigen Ghana. Als Nachfolger seines Onkels mütterlicherseits, Obiri Yeboah wurde Osei Tutu erst Kumasihene, also Herrscher der Stadt Kumasi, und 1695 der erste Asantehene, also Herrscher der Ashanti.

Osei Toutou, asantehene de la confédération Ashanti de 1695 à 1717).

Osei Kofi Tutu I był założycielem Konfederacji Aszanti, luźno połącznej grupy miast.