Opioid


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opioid
n. any substance similar to opium; natural substance produced in the body in response to stress or pain; synthetic drug with effects similar to those of opium
 
adj. having characteristics similar to that of opium; caused by an opioid peptide, caused by a substance produced in the body which has effects similar to that of opium


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Opioid
An opioid is a chemical substance that has a morphine-like action in the body. The main use is for pain relief. These agents work by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects, and the undesirable side effects. There are a number of broad classes of narcotics: natural opioids, alkaloids contained in the resin of the opium poppy including morphinecodeinethebaine, and oripavine;semi-synthetic opioids, created from the natural opioids, such as hydromorphonehydrocodoneoxycodone, and heroin;fully synthetic opioids, such as fentanylpethidinemethadone, and propoxyphene;endogenous opioid peptides, produced naturally in the body, such as endorphinsenkephalinsdynorphins, and endomorphins.
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NCI Dictionary of Cancer Terms Download this dictionary
opioid
A synthetic drug that is used to treat moderate to severe pain. Opioids are similar to opiates such as morphine and codeine.

A Service of the National Cancer Institute.

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