Oligonucleotide

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oligonucleotide
n. short chain of up to 20 nucleotides


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Oligonucleotide
Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesizers allow the synthesis of oligonucleotides up to 160 to 200 bases. The length of a synthesized base is usually denoted by 'mer' (from 'Greek' meros "part"). For example, a fragment of 25 bases would be called a 25-mer. Oligonucleotides are often used as probes for detecting complementary DNA or RNA because they bind readily to their complements. Examples of procedures that use oligonucleotides are DNA microarraysSouthern blotsfluorescent in situ hybridization (FISH), and the synthesis of artificial genes.
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Dictionary of MedicineDownload this dictionary
Oligonucleotide
A short DNA molecule composed of relatively few nucleotide bases.

Common Terms in Evolutionary Biology and Genetics DictionaryDownload this dictionary
Oligonucleotide
A short, synthetic DNA string used as a probe (as in SSOP) or primer (as in SSP) in molecular genetic studies.

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