John O'Brien may refer to: In public life:John O'Brien (businessman), Former UK Director of Passenger Rail Franchising
John O'Brien (politician), New Zealand political candidate and party leader
John O'Brien (UK politician), Far right figure, onetime leader of the British National Front John O'Brien (Washington State politician), former Representative and Speaker of the House in the Washington State Legislature
John F. O'Brien (1874–1939), New York Court of Appeals justice
John H. O'Brien, 4th Fire Commissioner of the City of New York
John P. O'Brien (1873-1951), Mayor of New York City
Ignatius O'Brien, 1st Baron Shandon (1857–1930), Lord Chancellor of Ireland from 1913 to 1918
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