The northern blot is a technique used in molecular biology research to study gene expression. It takes its name from the similarity of the procedure to the Southern blot procedure, named for biologist Edwin Southern, used to study DNA, with the key difference that, in the northern blot, RNA, rather than DNA, is the substance being analyzed by electrophoresis and detection with a hybridization probe. This technique was developed in 1977 by James Alwine, Kemp, and George Stark at Stanford University.
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A technique in molecular biology, used mainly to separate and identify pieces of RNA. Called a Northern blot because it is similar to a Southern blot (which is named after its inventor, the British biologist M.E. Southern).
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