Granulocyte Colony-Stimulating Factor (G-CSF or GCSF) is a hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to pulse them out of the marrow into the blood. It also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils.
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[noo-LA-stuh] A drug used to increase numbers of white blood cells in patients who are receiving chemotherapy. It belongs to the family of drugs called colony-stimulating factors. Also called pegfilgrastim and filgrastim-SD/01.
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