Hypertensive nephropathy (or "hypertensive nephrosclerosis", or "Hypertensive renal disease") is a medical condition referring to damage to the
kidney due to chronic
high blood pressure.It should be distinguished from "
renovascular hypertension" (I15.0), which is a form of
secondary hypertension.In the kidneys, as a result of benign
arterial hypertension,
hyaline (pink, amorphous, homogeneous material) accumulates in the wall of small arteries and arterioles, producing the thickening of their walls and the narrowing of the
lumens — hyaline
arteriolosclerosis. Consequent
ischemia will produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller
glomeruli with different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis. In advanced stages,
renal failure will occur. Functional nephrons have dilated tubules, often with hyaline
casts in the lumens.
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Hardening (sclerosis) of the kidney usually due to disease of the blood vessels in it from atherosclerosis.