Nalbuphine (nalbuphine hydrochloride) is a synthetic
opioid used commercially as an
analgesic under a variety of trade names, including Nubain. It is noteworthy in part for the fact that at low dosages, it is found much more effective by women than by men, and may even increase
pain in men, leading to its discontinuation in the UK in
2003.
See more at Wikipedia.org...