NMDA receptor antagonist

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the N-methyl d-aspartate receptor (NMDAR). They are used as anesthesia for animals and, less commonly, for humans; the state of anesthesia they induce is referred to as dissociative anesthesia. However, there is evidence that NMDA receptor antagonists can cause a certain type of brain damage referred to as Olney's Lesions (in rodents).
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NMDA antagonist Neurology Any of a number of agents that protect against brain damage in neurologic disorders–eg, stroke; [more]NMDA receptor antagonist - Community and Resources