Mutation rate

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Mutation rate
In genetics, the mutation rate is the chance of a mutation occurring in an organism or gene in each generation (or, in the case of multicellular organisms, cell division). See Luria-Delbrück experiment. The mutation frequency is the number of individuals in a population with a particular mutation, and tends to be reported more often as it is easier to measure (for instance, there is no need to restrict the population to experiencing only one generation, as needed to measure mutation rate). This is important in fields such as evolutionary biology and oncology.
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Mutation rate
The number of mutations at a particular locus which occur per gene per cell generation. This is the only source of variation in asexual organisms. The mutation rate is the likelihood of parentage when findings suggest otherwise. Beware of the different units in different mutation rates. In humans, the mutation rate is 1 bp per bp per cell division. This corresponds to mutations per gene per cell division and because there are divisions in a lifetime, mutations per gene per lifetime.


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