Ménétrier's disease (also known as hyperplastic hypersecretory gastropathy, and named after a French physician
Pierre Eugène Ménétrier, 1859-1935), is a disorder in which the
gastric mucosal folds (
rugae) are
enlarged (and the total weight of the stomach is increased), making the surface of the stomach look a bit like the
brain gyri. The altered gastric mucosa
secretes massive amounts of
mucus, resulting in low
plasma protein levels. The tissue may be inflamed and may contain ulcers. The disease also causes glands in the stomach to waste away and causes the body to lose fluid containing a protein called
albumin.
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