Systemic Lupus Erythematosus (SLE or lupus) is a chronic
autoimmune disease that can be fatal, though with recent medical advances fatalities are becoming increasingly rare. As with other
autoimmune diseases, the
immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the
heart,
joints,
skin,
lungs,
blood vessels,
liver,
kidneys and
nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-
European descent. Lupus is treatable
symptomatically, mainly with
corticosteroids and
immunosuppressants, though there is currently no cure. However, many people with Lupus lead long and substantial lives.
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