Lamictal
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Lamotrigine
Lamotrigine (marketed as Lamictal by
GlaxoSmithKline
, called Lamictin in
South Africa
, (Lamogine) in
Israel
, and in
South Korea
) is an
anticonvulsant
drug used in the treatment of
epilepsy
and
bipolar disorder
. For epilepsy it is used to treat
partial seizures
, primary and secondary
tonic-clonic seizure
s, and seizures associated with
Lennox-Gastaut syndrome
. Lamotrigine also acts as a
mood stabilizer
. It is the first medication since
lithium
granted
Food and Drug Administration
(FDA) approval for the maintenance treatment of
bipolar type I
. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown. Some think that it is a
Na
+
channel
blocker. It is inactivated by
hepatic
glucuronidation
.
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Lamictal
Lamictal® Lamotrigine Neurology An adjunct agent for treating generalized seizures in Lennox-Gastaut syndrome. See Lennox-Gastaut syndrome. [
more
]
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