Kartagener's syndrome

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Primary ciliary dyskinesia
Primary ciliary dyskinesia (PCD), also known as immotile ciliary syndrome or Kartagener Syndrome (KS), is a rare autosomal recessive genetic disorder caused by a defect in the action of the tiny hairs (cilia) lining the respiratory tract (lower and upper, sinuses, Eustachian tubemiddle ear) and fallopian tube. Specifically, it is a defect in a gene coding for left-right dynein (lrd), a key structural protein in cilia.
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Kartagener's syndrome
The trio of sinusitis, bronchitis and situs inversus (lateral reversal of the position all organs in the chest and abdomen with the heart and stomach on the right, the liver on the left, etc.--opposite or "inverted" from their usual position).


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