Erythromycin is a
macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of
penicillin, and is often used for people who have an
allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including
mycoplasma and
Legionellosis. It is also used to treat outbreaks of
chlamydia,
syphilis,
acne and
gonorrhea. Structurally, this macrocyclic compound contains a 14-membered
lactone ring with ten asymmetric centers and two sugars (L-cladinose and D-desoamine), making it a compound very difficult to produce via synthetic methods.
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