Hemophilia A

Haemophilia A (also spelled Hemophilia A or Hæmophilia A) is a blood clotting disorder caused by a mutation of the factor VIII gene, leading to a deficiency in Factor VIII. It is the most common hemophilia. Inheritance is X-linked recessive; hence, males are affected while females are carriers or very rarely display a mild phenotype. 1 in 5,000 males are affected.
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Hemophilia A n. Hemophilia due to deficiency of factor VIII, characterized by prolonged clotting time, decreased formation of thromboplastin, and [more]Hemophilia A - Community and Resources

Noun
1. hemophilia caused by a congenital deficiency of factor VIII; occurs almost exclusively in men
(synonym) haemophilia A, classical hemophilia, classical haemophilia
(hypernym) hemophilia, haemophilia, bleeder's disease

Classic hemophilia (the disease of the Russian royal house and other descendants of Queen Victoria). Due to profound deficiency of factor VIII which is necessary for normal blood clotting. The hemophilia A gene is on the X chromosome so females carry the gene and each of their sons stands a 50% chance of receiving the gene and having hemophilia. Treatment of hemophiliacs with contaminated blood products exposed many to HIV.

B: (Biologi) hemofili A
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