Hemolytic disease of the newborn

Hemolytic disease of the newborn, also known as HDN or Erythroblastosis fetalis, is an alloimmune condition that develops in a fetus, when the IgG antibodies that have been produced by the mother and have passed through the placenta include ones which attack the red blood cells in the fetal circulation. The red cells are broken down and the fetus can develop reticulocytosis and anemia. This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur. When the disease is moderate or severe, many erythroblasts are present in the fetal blood and so these forms of the disease can be called erythroblastosis fetalis (or erythroblastosis foetalis).
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Hemolytic disease of the newborn Also known as erythroblastosis neonatorum, this is a condition in which a newborn's red blood cells are destroyed [more]Hemolytic disease of the newborn - Community and Resources

Abnormal breakup of red blood cells in the fetus or newborn.