Hemoglobin S

Hemoglobin S n. Abbr. Hb S An abnormal hemoglobin in which valine has replaced glutamic acid causing the hemoglobin to become less soluble under [more]Hemoglobin S - Community and Resources

The most common type of abnormal hemoglobin, hemoglobin S is found in sickle cell trait and sickle cell anemia. It differs from hemoglobin A only by a single amino acid substitution. Recognition of this tiny change marked the opening of molecular medicine.