Gas exchange or respiration takes place at a respiratory surface - a boundary between the external environment and the interior of the body. For
unicellular organisms the respiratory surface is simply the
cell membrane, but for large organisms it usually is carried out in
respiratory systems. This name can cause problems - in biology the word "respiration" can mean
cellular respiration or
metabolism (ATP generation inside cells), however sometimes (such as here) it can also refer to
breathing (which is how the word is most often used by non-biologists).Gases cross the respiratory surface by
diffusion, so from
Fick's law we can predict that respiratory surfaces must have:a large surface areaa thin permeable surfacea moist exchange surface
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