The Fertility factor (also known as F factor or sex factor) is a
bacterial DNA sequence that allows a bacterium to produce a
sex pilus necessary for
conjugation. It contains 20 tra (for "transfer") genes and a number of other genetic sequences responsible for incompatibility,
replication, and other functions. The F factor is an
episome and can exist as an independent
plasmid or integrate into the bacterial cell's
genome. There are several names for the possible states:
Hfr bacteria possess F factor integrated into the bacterial
genome. F+ bacteria possess F factor as a plasmid independent of the bacterial genome. The F plasmid contains only F factor DNA and no DNA from the bacterial genome.F-prime bacteria possess an F plasmid that also includes some DNA taken from the bacterial genome.F- bacteria do not contain F factor.
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