Fulvestrant, also known as ICI 182,780, and "Faslodex" is a
drug treatment of hormone receptor-positive metastatic
breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an
estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. It is administered as a once-monthly injection.
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A drug that blocks estrogen activity in the body and is used in the treatment of estrogen-dependent tumors such as breast cancer. It belongs to the family of drugs called antiestrogens. Also called fulvestrant and ICI 182780.
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