Fanconi's anemia

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Fanconi anemia
Fanconi anemia (FA) is a  genetic disease that affects children and adults from all ethnic backgrounds. The disease is named after the Swiss pediatrician who originally described this disorder, Guido Fanconi. FA is characterized by short stature, skeletal anomalies, increased incidence of solid tumors and leukemias, bone marrow failure (aplastic anemia), and cellular sensitivity to DNA damaging agents such as mitomycin C.
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WordNet 2.0 DictionaryDownload this dictionary
Fanconi's anemia
Noun
1. a rare congenital anemia characterized by pancytopenia and hypoplasia of the bone marrow
(synonym) Fanconi's anaemia, congenital pancytopenia
(hypernym) anemia, anaemia



NCI Dictionary of Cancer Terms Download this dictionary
Fanconi's anemia
A rare and often fatal inherited disease in which the bone marrow fails to produce red blood cells, white blood cells, platelets, or a combination of these cells. The disease may transform into myelodysplastic syndrome or leukemia. Also called Fanconi's syndrome.

A Service of the National Cancer Institute.

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