Eloxatin
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Oxaliplatin
Oxaliplatin is a
platinum
-based
chemotherapy
drug
in the same family as
cisplatin
and
carboplatin
. It is typically administered in combination with
fluorouracil
and
leucovorin
in a combination known as
FOLFOX
for the treatment of
colorectal cancer
. Compared to cisplatin the two
amine
groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato
bidentate
derived from
oxalic acid
in order to improve water solubility.
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Eloxatin
Oxaliplatin Eloxitan Pharmacologic class: Alkylator Therapeutic class: Antineoplastic Pregnancy risk category D FDA Boxed Warning • Anaphylaxis may [
more
]
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