Eckstein is a surname of German origin, meaning "cornerstone" (eck means 'corner', and stein means 'stone'). According to information gleaned from the U.S. Census, around 2,500 people in the United States have the surname Eckstein. It may refer to the following people:
In sports:

• Bernd Eckstein, East German ski jumper who competed during the 1970s
• David Eckstein (born 1975), American professional baseball player
• Dieter Eckstein (born 1964), German football (soccer) player
• Hans Eckstein (1908–1985), German water polo player who competed in the 1932 Summer Olympics
• John Eckstein (German, 1736–1817), artist, active in Germany, London and Philadelphia
• Rudolf Eckstein (born 1915), German rower who competed in the 1936 Summer Olympics
• John Eckstein Artist, known for British Naval Portraits, died in Barbados