Cutaneous T-Cell lymphoma (CTCL) is a class of
non-Hodgkin's lymphoma, which is a type of
cancer of the
immune system. Unlike most non-Hodgkin's lymphomas (which are generally B-cell related), CTCL is caused by a mutation of
T cells. The
malignant T cells in the body are pushed to the surface of the
skin in a biological process used to rid the body of offending material, causing various
lesions to appear on the skin. These lesions change shape as the disease progresses, typically beginning as what appears to be a
rash and eventually forming plaques and
tumors before
metastatizing to other parts of the body.
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A disease in which certain cells of the lymph system (called T lymphocytes) become cancerous (malignant) and affect the skin.
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