Cl, Clx - Clearance - in volume/unit time - of a drug or chemical from a body fluid, usually plasma or blood, by specified route(s) and mechanism(s) of elimination, as indicated by a subscript, e.g., ClR, urinary
clearance; ClH, hepatic clearance, etc. ClT, total clearance, indicates clearance by all routes and mechanisms of biotransformation and excretion, operating simultaneously. ClT = kel ยท Vd. Following
intravenous administration, ClT = D/AUC; following administration of drug by any route other than the intravenous, ClT = F D/AUC.
Cf.
Clearance,
AUC,
F