Antisense RNA

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Antisense RNA
Antisense RNA (aRNA) is single-stranded RNA that is complementary to a messenger RNA (mRNA) strand transcribed within a cell. Antisense RNA may be introduced into a cell to inhibit translation of a complementary mRNA by base pairing to it and physically obstructing the translation machinery. This effect is therefore stoichiometric. An example of naturally occurring mRNA antisense mechanism is the hok/sok system of the E.coli R1 plasmid. Antisense RNA has long been thought of as a promising technique for disease therapy; the only such case to have reached the market is the drug fomivirsen.
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Antisense RNA
Antisense RNA an RNA sequence which is complementary to a functional RNA. [more]Antisense RNA - Community and Resources


Common Terms in Evolutionary Biology and Genetics DictionaryDownload this dictionary
Antisense RNA
Non-functional RNA which is complementary to an individual mRNA strand.

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