Antimicrobial peptides (also called host defence peptides) are an evolutionarily conserved component of the innate immune response and are found among all classes of life. These peptides are potent, broad spectrum
antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill
Gram negative and
Gram positive bacteria (including strains that are resistant to conventional antibiotics),
mycobacteria (including
Mycobacterium tuberculosis), enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears as though antimicrobial peptides may also have the ability to enhance immunity by functioning as
immunomodulators.
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