Angioid streaks

Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruch's membrane, an elastic tissue containing membrane of the retina that can become calcified and crack.They were first described by Robert Walter Doyne in 1889 in a patient with retinal hemorrhages. A few years later, ophthalmologist Hermann Jakob Knapp called them "angioid streaks" because of their resemblance to blood vessels. From histopathological research in the 1930s they were discovered to be caused by changes at the level of Bruch's membrane. Presently, it is believed that its pathology may be a combination of elastic degeneration of Bruch's membrane, iron deposition in elastic fibers from hemolysis with secondary mineralization, and impaired nutrition due to stasis and small vessel occlusion.
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Angioid streaks Gray, orange, or red wavy branching lines in Bruch's membrane. Mentioned in: Pseudoxanthoma Elasticum [more]Angioid streaks - Community and Resources

Tiny breaks in the elastin-filled tissue in the back of the eye (retinae). These abnormalities are visible to the doctor during an examination using a viewing instrument called an ophthalmoscope. Angioid streaks are seen in patients with pseudoxanthoma elasticum (abbreviated PXE), a rare disorder of degeneration of the elastic fibers with tiny areas of calcification in the skin, back of the eyes (retinae), and blood vessels. Angioid streaks can be associated with blindness