An Alu sequence is a short stretch of
DNA originally characterized by the action of the Alu
restriction endonuclease. Alu sequences of different kinds occur in large numbers in primate
genomes. In fact, Alu sequences are the most abundant mobile elements in the human genome. They are derived from the small cytoplasmic 7SL RNA, a component of the
signal recognition particle. The event, when a copy of the 7SL RNA became a precursor of the Alu sequence, took place in the genome of an ancestor of
Supraprimates.
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