Aetolia-Acarnania, (Greek: Αιτωλοακαρνανία, Aitoloakarnanía, also Aetoloacarnania and Etoloakarnania) is one of the prefectures of Greece. It is located in the western part of Greece; the prefecture is a combination of the regions Aetolia and Acarnania, and its capital for historical reasons is Mesolongi, with its biggest city and economic centre at Agrinion. The area is now connected with the Peloponnese peninsula via the spectacular Rio-Antirio Bridge, and the surrounding prefectures take in Arta in Epirus, a narrow length bordering Karditsa of Thessaly, Eurytania to the northeast, and Phocis to the east. This is the largest prefecture in Greece.
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