Addison's disease

Addison's disease (also known as chronic adrenal insufficiency,  hypocortisolism or hypocorticism) is a rare endocrine disorder in which the adrenal gland produces insufficient amounts of steroid hormones (glucocorticoids and often mineralocorticoids). It may develop in children as well as adults, and may occur as the result of a large number of underlying causes.
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Noun
1. a glandular disorder caused by failure of function of the cortex of the adrenal gland and marked by anemia and prostration with brownish skin
(synonym) Addison's syndrome, hypoadrenalism, hypoadrenocorticism
(hypernym) glandular disease, gland disease, glandular disorder, adenosis

A morbid condition causing a peculiar brownish discoloration of the skin, and thought, at one time, to be due to disease of the suprarenal capsules (two flat triangular bodies covering the upper part of the kidneys), but now known not to be dependent upon this causes exclusively. It is usually fatal.

  

noun
disease of the adrenal glands, resulting in general weakness, anaemia, low blood pressure and wasting away

Long-term underfunction of the outer portion of the adrenal gland. In medical terms, chronic insufficiency of the adrenal cortex. This may be due to a number of different insults to the adrenal including physical trauma, hemorrhage, and tuberculosis of the adrenal, and destruction of the cells in the pituitary gland that secrete ACTH (adrenocorticotropic hormone) which normally drives the adrenal. Addison’s disease is characterized by bronzing of the skin, anemia, weakness, and low blood pressure. The U.S. President J.F. Kennedy is said to have had Addison’s disease. Named after the British physician Thomas Addison (1793-1860).

n. โรคที่เกิดจากการบกพร่องของต่อมอดรีนัล(Adrenal)