ABI-007

Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute  in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'Taxol®'.
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A substance that is being studied in the treatment of cancer. It is a special form of the anticancer drug paclitaxel that may have fewer side effects and may be able to be given in higher doses. It belongs to the families of drugs called mitotic inhibitors and taxanes.