5P or 5-P may refer to:

• 5p, an arm of Chromosome 5 (human)
  • 5p- (or chromosome 5p deletion syndrome); see Cri du chat
• 5p, abbreviation for Five pence:
  • Five pence (British decimal coin)
  • Five pence (Irish decimal coin)
• GSAT-5P, an Indian communications satellite
• Team 5P, an animation production team
• Lim-5P, a model of PZL-Mielec Lim-6
• F9F-5P, a model of Grumman F9F Panther
• F6F-5P, a model of Grumman F6F Hellcat
• F4U-5P, a model of Vought F4U Corsair
• SV-5P, a model of Martin Marietta X-24A
• 5P Mara, a model of Dassault Mirage 5
• Typ 5P, a model of SEAT Toledo
• PI5P, abbreviation for Phosphatidylinositol 5-phosphate
• 5P, NASA ID for the Progress M-45 spacecraft
• 5P, a model of HP LaserJet 5

Cri du chat syndrome, also known as chromosome 5p deletion syndrome, 5p minus syndrome or Lejeune’s syndrome, is a rare genetic disorder due to a missing part of chromosome 5. Its name is a French term (cat-cry or call of the cat) referring to the characteristic cat-like cry of affected children. It was first described by Jérôme Lejeune in 1963. The condition affects an estimated 1 in 50,000 live births, strikes all ethnicities, and is more common in females by a 4:3 ratio.

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Five pence may refer to:

• Five pence (British decimal coin), a decimal subdivision of the pound sterling.
• Five pence (Irish decimal coin), a decimal subdivision of the now withdrawn Irish pound.

The British decimal five pence (5p) coin – often pronounced "five pee" – is a subdivision of pound sterling first issued on 23 April 1968 in preparation for the 1971 decimalisation of the currency. At that time it had the same value, size and weight as the existing shilling, and it may be viewed as a continuation of the older coin. Between 1968 and 1971 it circulated, with a value of one shilling, alongside the pre-decimal shilling coins – the aim being to gradually familiarise the public with the new decimal coinage. After decimalisation the old shilling coin continued in circulation, with a value of 5p, until finally withdrawn in 1990.