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4-NQO
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4-Nitroquinoline 1-oxide
4-Nitroquinoline 1-oxide (also known as 4-NQO, 4NQO, 4Nqo, NQO and NQNO) is a quinoline derivative and a tumorigenic compound used in the assessment of the efficacy of diets, drugs, and procedures in the prevention and treatment of cancer in animal models. It induces DNA lesions usually corrected by nucleotide excision repair.
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| NCI Dictionary of Cancer Terms | Download this dictionary |
4-NQO
4-nitroquinoline 1-oxide. A substance that is used in cancer research to cause tumors in laboratory animals. This is done to test new diets, drugs, and procedures for use in cancer prevention and treatment.
A Service of the National Cancer Institute.
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